A sister is more than just family—she’s a friend, a confidant, and often one of life’s greatest blessings. Whether she’s older, younger, or even a sister-in-faith, the bond shared with a sister is unique and irreplaceable. One of the most meaningful ways to show love and support for her is through prayer. A prayer for your sister isn’t just about asking God to bless her; it’s about lifting her up in faith, covering her with protection, and speaking life over her dreams, health, and happiness.
In a world filled with challenges, your sister needs encouragement and spiritual covering more than ever. Through prayer, you can ask God to guide her steps, strengthen her heart, and surround her with His peace and favor. Whether she’s walking through tough times or celebrating new beginnings, your prayers remind her that she is never alone. In this post, we’ll share heartfelt prayers for sisters—prayers of protection, blessing, and encouragement—that you can use to keep her uplifted every day.
23 Prayer For My Sister
1. Proverbs 17:17
A friend loves at all times, and a brother is born for adversity. (ESV)
Sisters are a special gift from God, offering love and support through every season of life. When we pray for our sisters, we ask God to strengthen the bond and bless their journey. Prayer becomes a way to cover them with divine protection and encouragement.
Lord, I thank You for my sister and the blessing she is in my life. Please watch over her today, guide her steps, and surround her with Your unfailing love. Help me to always support her in times of joy and adversity. Amen.
2. Jeremiah 29:11
For I know the plans I have for you, declares the Lord, plans for welfare and not for evil, to give you a future and a hope. (ESV)
God has a plan for each of our lives, including our sisters. His plans are filled with hope, peace, and purpose, even when challenges arise. Praying for our sisters reminds us to entrust their future into His capable hands.
Lord, I lift up my sister to You and ask that You lead her into the future You have planned. Fill her life with hope, peace, and opportunities that glorify You. Let her trust Your guidance and walk confidently in Your promises. Amen.
3. Psalm 121:7-8
The Lord will keep you from all evil; he will keep your life. The Lord will keep your going out and your coming in from this time forth and forevermore. (ESV)
God’s promise of protection is a comfort to those we love. Praying this over our sisters reminds us that He watches over their every step. His hand guards them in their daily lives, providing safety and peace.
Lord, please keep my sister safe in all she does. Protect her from harm, guide her in her daily path, and bless her with peace and strength. May she always find comfort in knowing You are near. Amen.
4. Philippians 4:13
I can do all things through Christ who strengthens me. (KJV)
Life can bring challenges that may feel overwhelming, but through Christ, strength is always available. When we pray this verse over our sisters, we ask God to empower them with endurance and faith. It is a reminder that they are never alone.
Lord, give my sister strength through every challenge she faces. Let her lean on You in moments of weakness and find courage in Your presence. May she always remember that her strength comes from Christ. Amen.
5. Numbers 6:24-26
The Lord bless you and keep you; the Lord make his face to shine upon you and be gracious to you; the Lord lift up his countenance upon you and give you peace. (ESV)
This blessing from Scripture is a timeless prayer we can pray over our sisters. It is a request for God’s favor, protection, and peace in their lives. Speaking this over them invites God’s presence into their everyday journey.
Lord, bless my sister with Your presence and grace. Shine Your light upon her, keep her safe, and grant her peace in every area of her life. May she always feel the warmth of Your love. Amen.
6. Isaiah 41:10
Fear not, for I am with you; be not dismayed, for I am your God; I will strengthen you, I will help you, I will uphold you with my righteous right hand. (ESV)
This verse reminds us that God is always near in times of fear and uncertainty. When we pray for our sisters, we can ask God to fill their hearts with courage and assurance. His strength sustains them through every trial.
Lord, please comfort my sister in moments of fear or doubt. Strengthen her with Your righteous hand and remind her that You are always with her. Fill her heart with peace and courage to face each day. Amen.
7. Psalm 20:4
May he grant you your heart’s desire and fulfill all your plans! (ESV)
God delights in blessing His children with the desires of their hearts when they align with His will. Praying this for our sisters is asking God to prosper their dreams and bring joy into their lives. It shows our love and hope for their future.
Lord, I pray that You grant my sister her heart’s desires as they align with Your will. Bless her plans and guide her toward opportunities that honor You. Let her life be filled with joy and fulfillment. Amen.
8. Colossians 3:15
And let the peace of Christ rule in your hearts, to which indeed you were called in one body. And be thankful. (ESV)
Peace is one of the greatest gifts we can ask for our sisters. God’s peace goes beyond understanding and brings calm to every situation. Praying for peace allows us to entrust their emotional and spiritual well-being to Him.
Lord, let the peace of Christ rule in my sister’s heart. Calm her worries, ease her burdens, and fill her with gratitude. May her life be a reflection of Your peace to those around her. Amen.
9. Ephesians 3:16-17
That he would grant you, according to the riches of his glory, to be strengthened with might by his Spirit in the inner man; that Christ may dwell in your hearts by faith. (KJV)
Spiritual strength comes from the indwelling presence of Christ. When we pray this over our sisters, we ask God to make them strong in faith. This strength sustains them not only in hard times but also in daily life.
Lord, strengthen my sister with Your Spirit and let Christ dwell richly in her heart. May her faith grow deeper every day and her life reflect Your love. Guide her to walk boldly in Your ways. Amen.
10. Psalm 91:11
For he will command his angels concerning you to guard you in all your ways. (ESV)
God’s angels are sent to watch over those He loves. This promise brings assurance when we pray for our sisters’ safety. His angelic protection covers every journey they take.
Lord, I ask You to command Your angels to guard my sister. Protect her in all her ways and keep her safe from harm. Let her always walk in the shelter of Your divine care. Amen.
11. Proverbs 3:5-6
Trust in the Lord with all your heart, and lean not on your own understanding. In all your ways acknowledge him, and he shall direct your paths. (KJV)
Trusting God brings guidance and clarity in every situation. When we pray this for our sisters, we ask God to lead them through life’s decisions with wisdom and discernment. It is a reminder to rely on His understanding rather than our own.
Lord, help my sister to trust You fully in all aspects of her life. Guide her steps, provide wisdom, and make her paths straight. Let her find comfort in knowing You are always directing her ways. Amen.
12. 2 Thessalonians 3:3
But the Lord is faithful, who shall stablish you, and keep you from evil. (KJV)
Faithfulness is a hallmark of God’s character. Praying this over our sisters asks God to establish their hearts and protect them from harm. His faithfulness provides security in uncertain times.
Lord, I pray that You keep my sister safe and steadfast. Protect her from evil and establish her in Your truth. May she rest in the assurance of Your faithful care. Amen.
13. Psalm 46:1
God is our refuge and strength, a very present help in trouble. (KJV)
Life brings challenges that can overwhelm the heart. Asking God to be a refuge for our sisters reminds them that He is always near in times of need. His strength enables them to overcome adversity.
Lord, be a refuge for my sister in every difficulty. Give her strength to endure challenges and comfort in moments of distress. Let her know that You are her ever-present help. Amen.
14. Isaiah 54:17
No weapon that is formed against thee shall prosper; and every tongue that shall rise against thee in judgment thou shalt condemn. (KJV)
God protects His children from harm and opposition. Praying this over our sisters is asking Him to defend them from spiritual, emotional, and physical threats. His power ensures victory over adversity.
Lord, protect my sister from all forms of harm. Let no weapon formed against her prosper, and defend her in every battle. Surround her with Your strength and divine protection. Amen.
15. 1 Thessalonians 5:16-18
Rejoice evermore. Pray without ceasing. In every thing give thanks: for this is the will of God in Christ Jesus concerning you. (KJV)
A life of gratitude and constant prayer strengthens the spirit. Praying this over our sisters invites joy, continuous communication with God, and a thankful heart. It cultivates resilience and faithfulness.
Lord, help my sister to rejoice, pray without ceasing, and give thanks in all circumstances. Let her life be full of joy and spiritual vitality. May she grow stronger in You each day. Amen.
16. Psalm 37:4
Delight thyself also in the Lord; and he shall give thee the desires of thine heart. (KJV)
God desires to fulfill the hearts of those who delight in Him. Praying this for our sisters asks God to align their desires with His will and bless them abundantly. It encourages faith and reliance on His timing.
Lord, help my sister to find delight in You above all else. Fulfill the desires of her heart that are in accordance with Your will. May her life reflect Your goodness and blessings. Amen.
17. Romans 15:13
Now the God of hope fill you with all joy and peace in believing, that ye may abound in hope, through the power of the Holy Ghost. (KJV)
Hope, joy, and peace are gifts from God through the Holy Spirit. When we pray this over our sisters, we ask God to fill them with encouragement and confidence in His promises. His presence brings reassurance and strength.
Lord, fill my sister with joy, peace, and hope through Your Spirit. Strengthen her faith and let her life overflow with Your blessings. Help her trust Your plan for her future. Amen.
18. Psalm 128:3-4
Thy wife shall be as a fruitful vine by the sides of thine house: thy children like olive plants round about thy table. (KJV)
Though this verse speaks of family, it reminds us of God’s blessing over relationships. Praying for our sisters includes asking God to bless them in their families, friendships, and personal growth. His favor enriches every area of their lives.
Lord, bless my sister abundantly in her relationships and family. Surround her with love, joy, and fruitfulness in all her endeavors. May her home and heart reflect Your blessings. Amen.
19. 1 Peter 5:7
Casting all your care upon him; for he careth for you. (KJV)
God’s care is constant and personal. Praying this for our sisters encourages them to release anxiety and trust in His loving provision. He invites us to cast every concern into His hands.
Lord, help my sister to cast all her worries upon You. May she find peace knowing that You care deeply for her. Strengthen her heart and sustain her through every challenge. Amen.
20. Deuteronomy 31:6
Be strong and of a good courage, fear not, nor be afraid of them: for the Lord thy God, he it is that doth go with thee; he will not fail thee, nor forsake thee. (KJV)
Courage is essential in navigating life’s uncertainties. Praying this over our sisters is asking God to embolden their hearts and give confidence in His constant presence. Fear loses power when God walks with us.
Lord, strengthen my sister with courage and faith. Remind her that You are always with her and will never forsake her. Let her face every challenge with confidence in Your support. Amen.
21. Proverbs 31:25
Strength and honor are her clothing; and she shall rejoice in time to come. (KJV)
This verse celebrates a woman of strength and dignity. When praying for our sisters, we ask God to clothe them in resilience, honor, and hope for the future. Their lives become a reflection of His glory.
Lord, clothe my sister with strength, dignity, and honor. Let her rejoice in the blessings You have prepared for her. May she shine as a testimony of Your grace and faithfulness. Amen.
22. John 15:12
This is my commandment, That ye love one another, as I have loved you. (KJV)
Love is central to Christian living. Praying for our sisters includes asking God to fill their hearts with love for others and deepen the love between siblings. This fosters harmony, understanding, and joy.
Lord, fill my sister’s heart with Your love. Help her to love others as You have loved her and strengthen our bond as siblings. Let her life radiate kindness, compassion, and grace. Amen.
23. Psalm 23:1-3
The Lord is my shepherd; I shall not want. He maketh me to lie down in green pastures: he leadeth me beside the still waters. He restoreth my soul: he leadeth me in the paths of righteousness for his name’s sake. (KJV)
This classic Psalm reminds us that God provides, guides, and restores. Praying this over our sisters is asking for provision, peace, and spiritual renewal in every area of their lives. God’s care nurtures both body and soul.
Lord, be the shepherd of my sister’s life. Provide for her needs, guide her steps, and restore her soul. Let her walk in Your paths of righteousness and experience Your peace every day. Amen.
Conclusion
Prayer for my sister is a tender act of love that entrusts her to God’s care each day. We ask for His protection, guidance, and strength over her choices, health, and relationships, believing He walks beside her through every trial and blessing.
Through prayer we commit her dreams to the Lord, pray for wisdom in decisions, courage in seasons of change, and peace that surpasses understanding. May God renew her hope daily, draw her closer to His purpose, and surround her with faithful friends and family who reflect His love. May His favor rest upon her now and always unceasingly.
